Catalytic role of the C-terminal domains of a fungal non-reducing polyketide synthase.
نویسندگان
چکیده
The in vivo activity of truncated forms of methylorcinaldehyde synthase shows that the synthase retains a hydrolytic release activity in the absence of reductive chain release and that chain-length is not controlled by the reductive release domain; experiments using a methyltransferase inhibitor suggest that methylation occurs prior to aromatisation.
منابع مشابه
Functional and Structural Analysis of Programmed C-Methylation in the Biosynthesis of the Fungal Polyketide Citrinin.
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عنوان ژورنال:
- Chemical communications
دوره 46 29 شماره
صفحات -
تاریخ انتشار 2010